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668270-12-0
Anti-Diabetic
C22H28N8O2
472.5 g/mol
Amorphous
Pipeline
Ready
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Linagliptin is an anti-diabetic drug, falling under the class of blood glucose lowering drugs. It is used to lower blood sugar levels in adults with type 2 diabetes mellitus, by increasing levels of natural substances called incretins, which help to control blood sugar by increasing insulin release. Over time, Linagliptin may also decrease your chances of heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage, eye problems, or gum disease. This drug can be used as monotherapy or in combination with other glucose lowering medicines. Linagliptin is administered through oral route by way of film-coated tablets.
Linagliptin is a competitive, reversible dipeptidyl peptidase 4 (DPP-4) inhibitor. Inhibition of this enzyme slows the breakdown of Glucagon-like peptide-1 (GLP-1) and Glucose-dependent insulinotropic polypeptide (GIP). GLP-1 and GIP stimulate the release of insulin from beta cells in the pancreas while inhibiting release of glucagon from pancreatic beta cells. These effects together reduce the breakdown of glycogen in the liver and increase insulin release in response to glucose. Thus, Linagliptin binds to DPP-4 in a reversible manner which increases the concentrations of incretin hormones.
Ornet Pharmaceuticals, based out of Gujarat, India, is a leading manufacturer and global supplier of Linagliptin API. Driven by technically sound, research-oriented leaders, each with over 2 decades of hands-on experience, Ornet develops and manufactures a wide array of complex APIs catering to multiple categories in its product portfolio, such as anti-diabetics, blood related, hormones, etc. Ornet’s Linagliptin API is the result of the “Quality over Quantity” approach taken by the organization for all R&D and manufacturing practices. This approach, along with the strategically located manufacturing facility in Gujarat, allows for Ornet to be a primary source, both domestically and globally, for all API needs.
The above-mentioned product is presented solely for informational purposes and does not constitute an offer in any sense. Products with Pipeline status may be under patent protection and are not offered until expiration of the corresponding IP right.
